二苯并环辛炔 (DBCO)
二苯并环辛炔 (DBCO)
DBCO (二苯并环辛炔, Dibenzocyclooctyne) 用于无需铜离子催化的叠氮-炔环加成 (SPAAC) 反应，该反应的二级反应动力学常数可达到 1。DBCO 系列产品包括可用于进一步连接的 DBCO-acid、DBCO-amine、DBCO-PEG-COOH、DBCO-PEG-amine，以及 DBCO 标记的 Biotin、荧光染料和生化小分子等。
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DBCO-acid
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DBCO-C6-acid
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DBCO-PEG3-acid
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DBCO-PEG4-acid
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DBCO-PEG5-acid
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DBCO-PEG12-acid
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DBCO-PEG24-acid
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DBCO-NHS ester
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DBCO-C6-NHS ester
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DBCO-PEG2-NHS ester
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DBCO-PEG3-NHS ester
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DBCO-PEG4-NHS ester
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DBCO-PEG5-NHS ester
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DBCO-PEG8-NHS ester
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DBCO-PEG12-NHS ester
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DBCO-PEG24-NHS ester
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DBCO-NHCO-PEG5-NHS ester
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DBCO-SS-COOH
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DBCO-CONH-S-S-NHS ester
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DBCO-Sulfo-NHS ester sodium
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Sulfo-DBCO-NHS ester
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DBCO-PEG16-NHS ester
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Sulpho-DBCO
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Sulpho-DBCO-NHS ester
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Sulfho-DBCO-PEG4-NHS eser
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Sulfho-DBCO-PEG4-COOH
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DBCO-PEG1-NHS ester
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DBCO-PEG4-TFP ester
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DBCO-C5-PEG4-NHS ester
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DBCO-C5-NHS ester
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DBCO-C5-acid
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DBCO-PEG11-OCH2-NHS ester
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DBCO-PEG9-OCH2-NHS ester
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DBCO-PEG3-OCH2-NHS ester
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DBCO-amine
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DBCO-C6-amine
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DBCO-C12-amine
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DBCO-PEG3-amine
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DBCO-PEG4-amine
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DBCO-PEG5-amine
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DBCO-PEG8-amine
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DBCO-PEG9-amine
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DBCO-PEG11-amine
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DBCO-PEG12-amine
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DBCO-PEG15-amine
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DBCO-PEG23-amine
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DBCO-PEG12-O-amine
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DBCO-PEG24-O-amine
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DBCO-SS-amine
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Sulfho-DBCO-PEG4-amine
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DBCO-PEG2-amine
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Sulfo-DBCO-amine
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DBCO-PEG6-amine
DBCO-荧光染料
DBCO (二苯并环辛炔) 标记的荧光染料，荧光染料包括：BODIPY、荧光素、罗丹明、花箐等常用商业染料，也包括在荧光成像中具有非常突出效果的 SiR 和 Alex Flour 647。 这些荧光探针可通过 DBCO 与 叠氮化合物的 SPAAC 反应实现对生化小分子的荧光示踪。
DBCO-生物素
DBCO (二苯并环辛炔) 标记的生物素 (Biotin)，中间的连接除了聚乙二醇外，还可包括在紫外光照射、还原等条件下可发生断裂的官能团。这些探针可通过 DBCO 与叠氮的 SPAAC 反应以及生物素与链霉亲和素 (streptavidin) 之间强亲和力实现对蛋白质的提取分离。
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(4E)-TCO-PEG11-DBCO
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(4E)-TCO-PEG23-DBCO
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(4E)-TCO-PEG4-DBCO
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Bis-Sulfone-PEG4-DBCO
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DBCO-DBCO
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DBCO-DPA-DC1
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DBCO-Palmitic
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DBCO-SS-DBCO
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DBCO-C6-NHCOCF3
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DBCO-TCO
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DBCO-四乙酰甘露糖胺
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DBCO-PEG2-DBCO
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DBCO-PEG3-F
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DBCO-PEG3-OTs
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DBCO-PEG4-Benzylamine
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DBCO-PEG4-DBCO
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DBCO-PEG4-Me-Tetrazine
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DBCO-PEG4-SS-PEG4-DBCO
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DBCO-PEG4-Tetrazine
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DBCO-PEG4-亚磷酰胺
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DBCO-PEG4-Palmitate
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DBCO-PEG4-Silane
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DBCO-PEG4-CONH-CH2CH2-CN
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DBCO-PEG5-Acrylate
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DBCO-PEG5-DBCO
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DBCO-PEG8-Benzylamine
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DBCO-PEG12-Tos
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DBCO-PEG16-Benzylamine
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mPEG2000-DBCO
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mPEG5000-DBCO
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DBCO-PEG20K-OMe
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DBCO-CONH-PEG4-NHCO-DBCO
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DBCO-NHCO-PEG4-NHBoc
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DBCO-N-ethyl-2-oxopropanamide
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Me-Tetrazine-DBCO
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m-PEG4-DBCO
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m-PEG8-DBCO
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m-PEG12-DBCO
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Oleic-DBCO
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Alendronate(ALD)-DBCO
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5,6-二氢二苯并[B,F]氮杂辛
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DBCO-PEG2-二茂铁
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m-PEG6-DBCO
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Sulfho-DBCO-Methyltetrazine
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Halo-DBCO
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DBCO-PEG3-VC-PAB-Exatecan
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DBCO-PEG3-Deferoxamine
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DBCO-PEG3-GGFG-Exatecan
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DBCO-PEG3-GGFG-MMAE
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CLS-PEG4-DBCO
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CLS-PEG2-DBCO
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H-D-Dap(DBCO)-OH
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DBCO-PEG3-GGFG-PNP
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DBCO-PEG3-EVC-MMAE
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DBCO-PEG3-EVC-Exatecan
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DNP-PEG4-DBCO
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DBCO-NHCO-PEG3-Fmoc
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DBCO-PEG2-NHBoc
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